I have Lubunutu running on my Asus TF300T and find it to be less than spectacular. You're VNCing into the X session so there is quite a bit of lag. It's a nifty toy, but I don't see doing anything too productive in it, and you certainly aren't going to play any fast-paced games. Some specific devices (Like the Acer Transformer tabs) have bootloaders for Arch, Debian, and Ubuntu. While I haven't gotten to try this yet, it's on my to-do list.