I haven't actually tried the emulator yet, but the comment on EA games taking forever to load reminded me of back in the mid 90s when Genesis/MD emulation was primitive and it too did that. Pretty much compatibility would go 1/1 for this, and I dunno if the emu has SRAM support (I assume not), but it just seemed fair to point out that some games won't develop glitches until well into the game - if they work. For example, Phantasy Star 4 - everything would in theory run great until you have to face a 'big' enemy (some that aren't normal sized). I think one or two later bosses are classified as this. Also I think the dialogue in the Molcum basement glitches about 50% or greater of the time, completely locking up the game.
But like I said, this is IF it works, and IF you can't save it wouldn't matter

(I'm talking about REALLY oldschool emulators like Genem and Megasis, not just Genecyst). So far emulation history has been a reliable benchmark for everything but NES.
What confuses me though is, why .smd format? Super Magic Drive format is considered outdated and virtually everything is .bin. I'm pretty sure .bin's are just raw dumps. It's a bit of a pain to convert them back from when I converted them for my DC! Oh well...